Calcium alginate hydrogel beads with high stiffness and extended dissolution behaviour
نویسندگان
چکیده
منابع مشابه
Fabrication of alginate hydrogel scaffolds and cell viability in calcium-crosslinked alginate hydrogel
................................................................................................................................... II DEDICATIONS ............................................................................................................................ III ACKNOWLEDGEMENTS ...........................................................................................................
متن کاملPreparation and Evaluation of Ketoprofen-loaded Calcium alginate beads
Ionotropic gelation method was used to entrap Ketoprofen (KP) into calcium alginate beads. KP is one of the non steroidal anti-inflammatory drugs (NSAIDs); it has a short half life (1.5-2 h) and deleterious side effects on GIT such as irritation and ulceration. Beads were investigated in-vitro for possible sustained drug release and in-vivo as a gastro-protective system for KP. The curing time ...
متن کاملThe drug release profile from calcium-induced alginate gel beads coated with an alginate hydrolysate.
Calcium-induced alginate gel bead (Alg-Ca) coated with an alginate hydrolysate (Alg), e.g. the guluronic acid block (GB) was prepared and the model drug, hydrocortisone release profiles were investigated under simulated gastrointestinal conditions. Their molecular weights were one sixth or one tenth that of Alg and the diffraction patterns of the hydrolysates resembled that of Alg. The drug rel...
متن کاملAddition of Fillers to Sodium Alginate Solution Improves Stability and Immobilization Capacity of the Resulting Calcium Alginate Beads
Background: Although advantages of immobilization of cells through entrapment in calcium alginate gel beads have already been demonstrated, nevertheless, instability of the beads and the mass transfer limitations remain as the major challenges.Objective: The objective of the present study was to increase the stability, porosity (reduce mass transfer limit...
متن کاملSimulation of Enzyme Catalysis in Calcium Alginate Beads
A general mathematical model for a fixed bed immobilized enzyme reactor was developed to simulate the process of diffusion and reaction inside the biocatalyst particle. The modeling and simulation of starch hydrolysis using immobilized α-amylase were used as a model for this study. Corn starch hydrolysis was carried out at a constant pH of 5.5 and temperature of 50°C. The substrate flow rate wa...
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ژورنال
عنوان ژورنال: European Polymer Journal
سال: 2016
ISSN: 0014-3057
DOI: 10.1016/j.eurpolymj.2015.12.029